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Article

Low CREBBP expression is associated with adverse long-term outcomes in paediatric acute lymphoblastic leukaemia.

European journal of haematology - 1 Aug 2017

Gao Chao, Zhang Rui-Dong, Liu Shu-Guang, Zhao Xiao-Xi, Cui Lei, Yue Zhi-Xia, Li Wei-Jing, Chen Zhen-Ping, Li Zhi-Gang, Rao Qing, Wang Min, Zheng Hu-Yong, Wang Jian-Xiang

Abstract excerpt

OBJECTIVES: CREBBP alterations are associated with many diseases including leukaemia. However, CREBBP expression and its clinical relevance in paediatric acute lymphoblastic leukaemia have not been elucidated. METHODS: We studied CREBBP mRNA expression in 349 patients treated with either the BCH-2003 or CCLG-2008 protocol. Using a receiver operating characteristic curve, patients were divided into low- or...

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Source

Identifiers

PMID: 28452416
DOI: 10.1111/ejh.12897

Genes

CREBBP
EFS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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