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Article

The 116G > A MSH6 and IVS1-1121C > T PMS2 Genes Polymorphisms Modulate the Risk of the Sporadic Colorectal Cancer Development in Polish Population.

Pathology oncology research : POR - 1 Apr 2018

Zelga Piotr, Przybyłowska-Sygut Karolina, Zelga Marta, Dziki Adam, Majsterek Ireneusz

Abstract excerpt

Colorectal cancer (CRC) is one of the most common cancers worldwide. DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects mismatches generated during DNA replication. MMR defects were found to be associated with hereditary non-polyposis colorectal cancer (HNPCC) and a subset of sporadic colon cancers. The inheritance of common variations in MMR genes may influences individual...

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Source

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Identifiers

PMID: 28451866
DOI: 10.1007/s12253-017-0231-5
PMCID: PMC5847625

Genes

PMS2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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