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Article

Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1 and BLM.

Carcinogenesis - 1 Mar 2010

Frank Bernd, Hoffmeister Michael, Klopp Norman, Illig Thomas, Chang-Claude Jenny, Brenner Hermann

Abstract excerpt

RecQ helicase family members are involved in multiple DNA repair pathways, protecting the genome from incorrect recombination during mitosis and maintaining its stability. Deficiencies in genes encoding the RecQ helicases WRN and BLM lead to rare autosomal recessive diseases, Werner and Bloom syn...

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Source

Identifiers

PMID: 19945966
DOI: 10.1093/carcin/bgp293

Genes

BLM
WRN
RMI1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19945966-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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