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Article

Molecular analysis of imperative polymorphisms of MLH1 gene in sporadic colorectal cancer.

Cancer biomarkers : section A of Disease markers - 1 Jan 2013

Milanizadeh Saman, Khanyaghma Mahsa, Haghighi Mahdi Montazer, Mohebbi Seyedreza, Damavand Behzad, Almasi Shohreh, Azimzadeh Pedram, Zali Mohammadreza

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms in mismatch repair genes may be associated with different protein expression, production, and efficiency according to allele status and influence the risk of developing colorectal cancer. OBJECTIVE: This research aimed at analyzing two important polymorphisms in MLH1 gene and their association in colorectal cancer susceptibility. METHODS: In total, 219 CRC patients and...

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Source

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Identifiers

PMID: 24595079
DOI: 10.3233/CBM-140391
PMCID: PMC12928317

Genes

MLH1

Provenance

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