Article
Molecular analysis of MLH1 variants in Chinese sporadic colorectal cancer patients.
Genetics and molecular research : GMR - 26 Apr 2016
Peng H X, Xu X, Yang R, Chu Y M, Yang D M, Xu Y, Zhou F L, Ma W Z, Zhang X J, Guan M, Yang Z H, Jin Z D
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in mismatch repair genes, especially in the MLH1 gene, are closely associated with susceptibility to hereditary nonpolyposis colorectal cancer. However, few relevant findings are available regarding the association between sporadic colorectal cancer (SCRC) and SNPs of MLH1 in Chinese patients. Therefore, the present study aimed to describe the pathogenic association between...
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