Article
Genetic susceptibility to infectious diseases: Current status and future perspectives from genome-wide approaches.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2018
Mozzi Alessandra, Pontremoli Chiara, Sironi Manuela
Abstract excerpt
Genome-wide association studies (GWASs) have been widely applied to identify genetic factors that affect complex diseases or traits. Presently, the GWAS Catalog includes >2800 human studies. Of these, only a minority have investigated the susceptibility to infectious diseases or the response to therapies for the treatment or prevention of infections. Despite their limited application in the field, GWASs have...
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