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Article

HLA and infectious diseases.

Clinical microbiology reviews - 1 Apr 2009

Blackwell Jenefer M, Jamieson Sarra E, Burgner David

Abstract excerpt

Following their discovery in the early 1970s, classical human leukocyte antigen (HLA) loci have been the prototypical candidates for genetic susceptibility to infectious disease. Indeed, the original hypothesis for the extreme variability observed at HLA loci (H-2 in mice) was the major selective pressure from infectious diseases. Now that both the human genome and the molecular basis of innate and acquired...

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Identifiers

PMID: 19366919
DOI: 10.1128/CMR.00048-08
PMCID: PMC2668228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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