Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic impact of chromosomal aberrations and GNAQ, GNA11 and BAP1 mutations in uveal melanoma.

Acta ophthalmologica - 1 Feb 2018

Staby Kjersti M, Gravdal Karsten, Mørk Sverre J, Heegaard Steffen, Vintermyr Olav K, Krohn Jørgen

Abstract excerpt

PURPOSE: To evaluate clinico-pathological and molecular prognostic factors in a well-defined series of posterior uveal melanoma (UM) with focus on chromosomal aberrations and mutations in the GNAQ, GNA11 and BRCA1-associated protein 1 (BAP1) genes. METHODS: Formalin-fixed paraffin-embedded (FFPE) tissue samples were obtained from 50 consecutive eyes enucleated for UM between 1993 and 2005. The material was tested...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 3
Share to GTP-Binding Protein alpha Subunits

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits, Gq-G11

Share to Multiplex Polymerase Chain Reaction

Share to Neoplasm Metastasis

Share to Ubiquitin Thiolesterase

Share to Uveal Melanoma

Share to Uveal Neoplasms

Source

Identifiers

PMID: 28444874
DOI: 10.1111/aos.13452

Genes

BAP1
GNA11
GNAQ
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic impact of chromosomal aberrations and GNAQ, GNA11 and BAP1 mutations in uveal melanoma.PMID 28444874Read ↗

Prognostic value of chromosomal imbalances, gene mutations, and BAP1 expression in uveal melanoma.Semantic proximity Read ↗

Correlation between BAP1 Localization, Driver Mutations, and Patient Survival in Uveal MelanomaSemantic proximity Read ↗

Driver Mutations in Uveal Melanoma: Associations With Gene Expression Profile and Patient Outcomes.Semantic proximity Read ↗

Genetics and RNA Regulation of Uveal MelanomaSemantic proximity Read ↗

Current molecular and clinical insights into uveal melanoma (Review).Semantic proximity Read ↗

Metastatic Disease in Polyploid Uveal Melanoma Patients Is Associated With BAP1 Mutations.Semantic proximity Read ↗

The genetics of uveal melanoma: an emerging framework for targeted therapy.Semantic proximity Read ↗

Molecular profiling of primary uveal melanoma: results of a Polish cohort.Semantic proximity Read ↗

Genetic landscape of uveal melanoma.Semantic proximity Read ↗

Uveal Melanoma: Molecular and Genetic Mechanisms of Development and Therapeutic ApproachesSemantic proximity Read ↗

Clinical significance of immunohistochemistry for detection of BAP1 mutations in uveal melanoma.Semantic proximity Read ↗

Immunohistochemical and molecular profiling of uveal melanoma: clinicopathological correlations from an Italian cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.