Article
Immunohistochemical and molecular profiling of uveal melanoma: clinicopathological correlations from an Italian cohort.
Pathologica - 1 Dec 2025
Fortarezza Francesco, Zarrilli Giovanni, Munari Giada, Angerilli Valentina, Balistreri Mariangela, Piccin Luisa, Salizzato Valentina, Pigozzo Jacopo, Midena Giulia, Parrozzani Raffaele, Guarneri Valentina, Midena Edoardo, Sbaraglia Marta, Fassan Matteo, Dei Tos Angelo Paolo
Abstract excerpt
Objective: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, characterized by distinct histopathological and molecular features and often associated with poor prognosis due to its high metastatic potential. While histology, BAP1 status, and chromosomal changes are established prognostic markers, integration of morphological, immunophenotypic, and molecular data is evolving. Methods:...
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