Article
TLR3 polymorphisms are associated with the severity of hand, foot, and mouth disease caused by enterovirus A71 in a Chinese children population.
Journal of medical virology - 1 Nov 2021
Chen Guo-Ping, Xiang Kun, Sun Liang, Shi Yong-Lin, Meng Can, Song Lv, Liu Rui-Shan, Li Wei-Dong, Pan Hai-Feng
Abstract excerpt
Hand, foot, and mouth disease (HFMD) caused by enterovirus A71 (EV-A71) is a contagious viral disease, and toll-like receptors (TLRs) play essential roles in resisting the pathogen. The aim of this study was to assess the potential relationship between several TLRs polymorphisms and the HFMD severity in a Chinese children population. A total of 328 Chinese children with HFMD were included in the present study....
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