Article
Association of Interleukin-17F gene polymorphisms with susceptibility to severe enterovirus 71 infection in Chinese children.
Archives of virology - 1 Jul 2018
Li Fei, Liu Peipei, Guo Ya, Han Zhenliang, Liu Yedan, Wang Yuanyuan, Song Long, Cheng Jianguo, Chen Zongbo
Abstract excerpt
Enterovirus 71 (EV71) is a single-strand RNA virus that causes hand, foot and mouth disease (HFMD) in infants and young children, leading to neurological complications with significant morbidity and mortality. Unfortunately, the pathogenesis of EV71 infection is not well understood. In this study, we investigated the IL-17F rs1889570 and rs4715290 gene polymorphisms in a Chinese Han population. Severe cases and...
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