Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life.

doi:10.1080/15622975.2017.1322219

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Article

Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jun 2019

Moreira Estefania Gastaldello, Correia Dalmo Guilherme, Bonifácio Kamila Landucci, Moraes Juliana Brum de, Cavicchioli Fernanda Liboni, Nunes Carolina Sampaio, Nunes Sandra Odebrecht Vargas, Vargas Heber Odebrecht, Barbosa Décio Sabbatini, Maes Michael

Abstract excerpt

Objectives: Mood disorders (MDs) frequently co-exist with cardiovascular disease (CVD) and immune-inflammatory and oxidative stress are important shared pathophysiological pathways. Even though there has been an extensive investigation of the enzyme paraoxonase 1 (PON1) as a biomarker of susceptibility for CVD, there are few reports studying PON1 in MDs. The aim of this study was to determine the association...

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Identifiers

PMID: 28441923
DOI: 10.1080/15622975.2017.1322219

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PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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