Article
Paraoxonase 1 status and interactions between Q192R functional genotypes by smoking contribute significantly to total plasma radical trapping antioxidant potential.
Neuroscience letters - 3 Oct 2014
Bortolasci Chiara Cristina, Maes Michael, Vargas Heber Odebrecht, Souza-Nogueira André, Moreira Estefania Gastaldello, Nunes Sandra Odebrecht Vargas, Berk Michael, Dodd Seetal, Barbosa Décio Sabbatini
Abstract excerpt
The measurement of the total radical trapping antioxidant potential (TRAP) is a general marker of peripheral blood antioxidant defenses. Paraoxonase 1 (PON1) is a potent antioxidant, which protects against lipid peroxidation. The study aimed to examine the relation between TRAP levels and PON1 activity, PON1 Q192R functional genotypes, smoking, interactions between PON1 genotypes and smoking, and mood disorders,...
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