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Article

Tumor Suppressor PTPRJ Is a Target of miR‐155 in Colorectal Cancer

19 Mar 2017

Abstract excerpt

PTPRJ is known for its antiproliferative role. Loss of heterozygosity (LOH) of PTPRJ has frequently been observed in various human cancers including colorectal cancer (CRC), lung cancer, and breast cancer. However, the function and mechanism of PTPRJ in CRC are not well understood. At the present study, we show that ectopic expression of PTPRJ inhibits cell growth, migration, and invasiveness in CRC cell line...

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PMID: 28316102
DOI: 10.1002/jcb.25995

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