Article
Effect of ERCC1 polymorphisms on the response to platinum-based chemotherapy: A systematic review and meta-analysis based on Asian population.
PloS one - 1 Jan 2023
Wu Xiaoqing, Lu Wenping, Jiang Cuihong, Zhang Dongni, Zhang Weixuan, Cui Yongjia, Zhuo Zhili, Mei Heting, Wang Ya'nan, Zhang Mengfan, Chen Shuntai
Abstract excerpt
BACKGROUND: Platinum-based chemotherapy is one of the most common treatments for many cancers; however, the effect of chemotherapy varies from individual to individual. Excision repair cross complementation group 1 (ERCC1) is widely recognized as a key gene regulating nucleotide excision repair (NER) and is closely associated with platinum response. Many studies have yielded conflicting results regarding whether...
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