Article
Contribution of common genetic variants to obesity and obesity-related traits in mexican children and adults.
PloS one - 1 Jan 2013
León-Mimila Paola, Villamil-Ramírez Hugo, Villalobos-Comparán Marisela, Villarreal-Molina Teresa, Romero-Hidalgo Sandra, López-Contreras Blanca, Gutiérrez-Vidal Roxana, Vega-Badillo Joel, Jacobo-Albavera Leonor, Posadas-Romeros Carlos, Canizalez-Román Adrián, Río-Navarro Blanca Del, Campos-Pérez Francisco, Acuña-Alonzo Victor, Aguilar-Salinas Carlos, Canizales-Quinteros Samuel
Abstract excerpt
BACKGROUND: Several studies have identified multiple obesity-associated loci mainly in European populations. However, their contribution to obesity in other ethnicities such as Mexicans is largely unknown. The aim of this study was to examine 26 obesity-associated single-nucleotide polymorphisms (SNP) in a sample of Mexican mestizos. METHODS: 9 SNPs in biological candidate genes showing replications (PPARG,...
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