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Article

Network-assisted analysis of GWAS data identifies a functionally-relevant gene module for childhood-onset asthma

11 Apr 2017

Abstract excerpt

Abstract The number of genetic factors associated with asthma remains limited. To identify new genes with an undetected individual effect but collectively influencing asthma risk, we conducted a network-assisted analysis that integrates outcomes of genome-wide association studies (GWAS) and protein-protein interaction networks. We used two GWAS datasets, each consisting of the results of a meta-analysis of nine...

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PMID: 28428554
DOI: 10.1038/s41598-017-01058-y

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