Article
Association between BRCA1 P871L polymorphism and cancer risk: evidence from a meta-analysis.
Oncotarget - 2 May 2017
Miao Limin, Yu Yang, Ji Yefeng, Zhang Bo, Yuan Zhiyao, Du Yifei, Zhu Longbiao, Wang Ruixia, Chen Ning, Yuan Hua
Abstract excerpt
Breast cancer 1 (BRCA1) gene makes great contributions to the repair of DNA. The association between BRCA1 P871L polymorphism and cancer risk has been investigated in a growing number of studies, but the conclusions are not conclusive. To obtain a comprehensive conclusion, we performed a meta-analysis of 24 studies with 13762 cases and 22388 controls. The pooled results indicated that BRCA1 gene P871L variant...
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