Article
Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2017
Avigdor Bracha Erlanger, Beierl Katie, Gocke Christopher D, Zabransky Daniel J, Cravero Karen, Kyker-Snowman Kelly, Button Berry, Chu David, Croessmann Sarah, Cochran Rory L, Connolly Roisin M, Park Ben H, Wheelan Sarah J, Cimino-Mathews Ashley
Abstract excerpt
Purpose: Although most human cancers display a single histology, there are unusual cases where two or more distinct tissue types present within a primary tumor. One such example is metaplastic breast carcinoma, a rare but aggressive cancer with a heterogeneous histology, including squamous, chondroid, and spindle cells. Metaplastic carcinomas often contain an admixed conventional ductal invasive or in situ...
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