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Transcriptomic alterations underlying metaplasia into specific metaplastic components in metaplastic breast carcinoma

27 Jan 2023

Abstract excerpt

BACKGROUND: Metaplastic breast carcinoma (MpBC) typically consists of carcinoma of no special type (NST) with various metaplastic components. Although previous transcriptomic and proteomic studies have reported subtype-related heterogeneity, the intracase transcriptomic alterations between metaplastic components and paired NST components, which are critical for understanding the pathogenesis underlying the...

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PMID: 36707876
DOI: 10.1186/s13058-023-01608-5

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