Article
Identification of common variants in BRCA2 and MAP2K4 for susceptibility to sporadic pancreatic cancer.
Carcinogenesis - 1 May 2013
Huang Liming, Wu Chen, Yu Dianke, Wang Chengfeng, Che Xu, Miao Xiaoping, Zhai Kan, Chang Jiang, Jiang Guoliang, Yang Xianghong, Cao Guangwen, Hu Zhibin, Zhou Yongjian, Zuo Chaohui, Wang Chunyou, Zhang Xianghong, Zhou Yifeng, Yu Xianjun, Dai Wanjin, Li Zhaoshen, Shen Hongbing, Liu Luming, Chen Yanling, Zhang Sheng, Wang Xiaoqi, Liu Yu, Sun Menghong, Cao Wei, Gao Jun, Ma Ying, Zheng Xiongwei, Cheung Siu Tim, Jia Yongfeng, Tan Wen, Wu Tangchun, Lin Dongxin
Abstract excerpt
Germline mutations in genes that cause hereditary syndromes are highly predisposed to familial pancreatic cancer. However, genetic susceptibility to sporadic pancreatic cancer is largely uncovered. We conducted a two-stage association study on pancreatic cancer that included 981 cases and 1991 controls in the first stage followed by a second stage (2603 cases and 2877 controls). Using an approach based on...
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