Article
Impact of genetic variants of ABCB1, APOB, CAV1, and NAMPT on susceptibility to pancreatic ductal adenocarcinoma in Chinese patients.
Molecular genetics & genomic medicine - 1 Jun 2020
Li Baohuan, Zhang Chuanzhen, Wang Jingjing, Zhang Meijuan, Liu Changhong, Chen Ziping
Abstract excerpt
BACKGROUND: Among the different types of cancer, pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is the most lethal malignancy, with poor early detection rates and prognosis. The aim of the present study was to investigate the potential genetic effects of the single-nucleotide polymorphisms (SNPs) in ABCB1 (rs1045642, rs3789243, rs4148737), APOB (rs693, rs1042031), CAV1 (,...