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Article

Purification of leukemic blast cells from blood smears using laser microdissection.

International journal of hematology - 1 Jul 2017

Matsuo Hidemasa, Shiga Shuichi, Imai Tsuyoshi, Kamikubo Yasuhiko, Toki Tsutomu, Terui Kiminori, Ito Etsuro, Adachi Souichi

Abstract excerpt

In treatment of acute myeloid leukemia (AML), prognostic factors, including gene mutation and abnormal gene expression, enable risk stratification of patients. However, in the case of a small proportion of leukemic blast cells, such as AML associated with Down syndrome (AML-DS), it is not possible to examine prognostic factors precisely due to the large proportion of normal cells. Here, we present a novel method...

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PMID: 28409329
DOI: 10.1007/s12185-017-2227-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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