Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-resolution analysis of aberrant regions in autosomal chromosomes in human leukemia THP-1 cell line

1 Jan 2009

Abstract excerpt

BACKGROUND: THP-1 is a human monocytic leukemia cell line derived from a patient with acute monocytic leukemia. The cell line differentiates into macrophage-like cells by stimulation with phorbol myristate acetate (PMA). Although it has been used frequently as a model for macrophage differentiation in research including the FANTOM4/Genome Network Project, there are few reports on its genomic constitution....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Acute Myeloid Leukemia Research
Share to Genomic variations and chromosomal abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19635138
DOI: 10.1186/1756-0500-2-153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-resolution analysis of aberrant regions in autosomal chromosomes in human leukemia THP-1 cell linePMID 19635138Read ↗

Monocytic THP-1 Cells Diverge Significantly From Their Native Counterparts: A Comparative Examination of The Chromosomal Conformations And TranscriptomesSemantic proximity Read ↗

Evaluation of 17 genetic variants in association with leukemia in the north Indian population using MassARRAY Sequenom.Semantic proximity Read ↗

Pathways related to PMA-differentiated THP1 human monocytic leukemia cells revealed by RNA-SeqSemantic proximity Read ↗

Multi-omic analysis of chronic myelomonocytic leukemia monocytes reveals metabolic and immune dysregulation leading to altered macrophage polarizationSemantic proximity Read ↗

Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with anMLL-AF9 translocationSemantic proximity Read ↗

Array CGH in human leukemia: from somatics to genetics.Semantic proximity Read ↗

Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignancies.Semantic proximity Read ↗

Use of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemia.Semantic proximity Read ↗

A dynamic database of microarray-characterized cell lines with various cytogenetic and genomic backgrounds.Semantic proximity Read ↗

Identified hidden genomic changes in mantle cell lymphoma using high-resolution single nucleotide polymorphism genomic array.Semantic proximity Read ↗

Development and validation of a CGH microarray for clinical cytogenetic diagnosisSemantic proximity Read ↗

High-resolution oligonucleotide array-CGH pinpoints genes involved in cryptic losses in chronic lymphocytic leukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.