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Article

Unique invariant natural killer T cells promote intestinal polyps by suppressing TH1 immunity and promoting regulatory T cells.

Mucosal immunology - 1 Jan 2018

Wang Y, Sedimbi S, Löfbom L, Singh A K, Porcelli S A, Cardell S L

Abstract excerpt

CD1d-restricted invariant natural killer T (iNKT) cells are known as potent early regulatory cells of immune responses. Besides the established roles in the regulation of inflammation and autoimmune disease, studies have shown that iNKT cells have important roles in tumor surveillance and the control of tumor metastasis. Here we found that the absence of iNKT cells markedly decreased the total number of...

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Identifiers

PMID: 28401935
DOI: 10.1038/mi.2017.34
PMCID: PMC5638666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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