Article
Methylation matters: FK506 binding protein 51 (FKBP5) methylation moderates the associations of FKBP5 genotype and resistant attachment with stress regulation.
Development and psychopathology - 1 May 2017
Mulder Rosa H, Rijlaarsdam Jolien, Luijk Maartje P C M, Verhulst Frank C, Felix Janine F, Tiemeier Henning, Bakermans-Kranenburg Marian J, Van Ijzendoorn Marinus H
Abstract excerpt
The parent-child attachment relationship plays an important role in the development of the infant's stress regulation system. However, genetic and epigenetic factors such as FK506 binding protein 51 (FKBP5) genotype and DNA methylation have also been associated with hypothalamus-pituitary-adrenal axis functioning. In the current study, we examined how parent-child dyadic regulation works in concert with genetic...
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