Article
FKBP5 and resistant attachment predict cortisol reactivity in infants: gene-environment interaction.
Psychoneuroendocrinology - 1 Nov 2010
Luijk Maartje P C M, Velders Fleur P, Tharner Anne, van Ijzendoorn Marinus H, Bakermans-Kranenburg Marian J, Jaddoe Vincent W V, Hofman Albert, Verhulst Frank C, Tiemeier Henning
Abstract excerpt
Quality of the parent-infant attachment relationship influences physiological stress regulation. Genetic factors also contribute to the stress regulatory HPA-axis. Quality of attachment as an index of the rearing environment (measured with the Strange Situation Procedure, SSP), and HPA-axis related SNPs (BclI, rs41423247; TthIIII, rs10052957; GR-9β, rs6198; N363S, rs6195; ER22/23EK, rs6189 and 6190; and FKBP5,...