Article
The early care environment and DNA methylome variation in childhood.
Development and psychopathology - 1 Aug 2018
Garg Elika, Chen Li, Nguyen Thao T T, Pokhvisneva Irina, Chen Lawrence M, Unternaehrer Eva, MacIsaac Julia L, McEwen Lisa M, Mah Sarah M, Gaudreau Helene, Levitan Robert, Moss Ellen, Sokolowski Marla B, Kennedy James L, Steiner Meir S, Meaney Michael J, Holbrook Joanna D, Silveira Patricia P, Karnani Neerja, Kobor Michael S, O'Donnell Kieran J
Abstract excerpt
Prenatal adversity shapes child neurodevelopment and risk for later mental health problems. The quality of the early care environment can buffer some of the negative effects of prenatal adversity on child development. Retrospective studies, in adult samples, highlight epigenetic modifications as sentinel markers of the quality of the early care environment; however, comparable data from pediatric cohorts are...
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