Article
Change in FK506 binding protein 5 (FKBP5) methylation over time among preschoolers with adversity.
Development and psychopathology - 1 Dec 2017
Parade Stephanie H, Parent Justin, Rabemananjara Kantoniony, Seifer Ronald, Marsit Carmen J, Yang Bao-Zhu, Zhang Huiping, Tyrka Audrey R
Abstract excerpt
FK506 binding protein 5 (FKBP5) alters stress response system functioning, and childhood maltreatment is associated with methylation of the FKBP5 gene. Yet it is unknown if maltreatment contributes to change in FKBP5 methylation over time. The current study draws upon a sample of 231 preschoolers, including 123 with child welfare documentation of moderate to severe maltreatment in the past 6 months, to understand...
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