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Article

Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior

25 Mar 2016

Abstract excerpt

OBJECTIVE: Increased risk of psychopathology is observed in children exposed to maternal prenatal distress, and elevated maternal cortisol and epigenetic regulation of placental glucocorticoid-pathway genes are potential mechanisms. The authors examined maternal distress and salivary cortisol in relation to fetal movement and heart rate ("coupling") and DNA methylation of three glucocorticoid pathway...

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Share to Maternal Mental Health During Pregnancy and Postpartum
Share to Neuroendocrine regulation and behavior
Share to Stress Responses and Cortisol

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Identifiers

PMID: 27013342
DOI: 10.1176/appi.ajp.2015.15091171

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