Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition.

JAMA - 11 Apr 2017

Gottesman Rebecca F, Schneider Andrea L C, Zhou Yun, Coresh Josef, Green Edward, Gupta Naresh, Knopman David S, Mintz Akiva, Rahmim Arman, Sharrett A Richey, Wagenknecht Lynne E, Wong Dean F, Mosley Thomas H

Abstract excerpt

IMPORTANCE: Midlife vascular risk factors have been associated with late-life dementia. Whether these risk factors directly contribute to brain amyloid deposition is less well understood. OBJECTIVE: To determine if midlife vascular risk factors are associated with late-life brain amyloid deposition, measured using florbetapir positron emission tomography (PET). DESIGN, SETTING, AND PARTICIPANTS: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid
Share to Aniline Compounds

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black People

Share to Dementia

Share to Diabetes Complications

Share to Hypercholesterolemia

Share to Hypertension

Share to Positron-Emission Tomography

Source

Open in PubMed Open full text

Identifiers

PMID: 28399252
DOI: 10.1001/jama.2017.3090
PMCID: PMC5921896

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition.PMID 28399252Read ↗

The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE.Semantic proximity Read ↗

Lipids, lipoproteins, and apolipoproteins: Associations with cognition and dementiaSemantic proximity Read ↗

Midlife insulin resistance, APOE genotype, and late-life brain amyloid accumulation.Semantic proximity Read ↗

Cross-sectional associations between lifecourse dementia risk factors, plasma neurodegenerative biomarkers, and cognition in older adults in IndiaSemantic proximity Read ↗

Genetic Risk for Alzheimer Disease, Midlife Hypertension, and Dementia: The ARIC Neurocognitive Study.Semantic proximity Read ↗

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study.Semantic proximity Read ↗

Atherosclerosis and risk for dementia.Semantic proximity Read ↗

Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology.Semantic proximity Read ↗

Midlife insulin resistance, APOE genotype, and change in late-life brain beta-amyloid accumulation - A 5-year follow-up [11C]PIB-PET study.Semantic proximity Read ↗

Vascular burden and Alzheimer disease pathologic progression.Semantic proximity Read ↗

Multidomain determinants of perivascular spaces indicate early cerebrovascular vulnerability in individuals at risk of Alzheimer’s diseaseSemantic proximity Read ↗

Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.