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Article

Examination of bedaquiline- and linezolid-resistant Mycobacterium tuberculosis isolates from the Moscow region.

The Journal of antimicrobial chemotherapy - 1 Jul 2017

Zimenkov Danila V, Nosova Elena Yu, Kulagina Elena V, Antonova Olga V, Arslanbaeva Liaisan R, Isakova Alexandra I, Krylova Ludmila Yu, Peretokina Irina V, Makarova Marina V, Safonova Svetlana G, Borisov Sergey E, Gryadunov Dmitry A

Abstract excerpt

Objectives: To study the isolates with acquired resistance to bedaquiline and linezolid that were obtained from patients enrolled in a clinical study of a novel therapy regimen for drug-resistant TB in Moscow, Russia. Methods: Linezolid resistance was detected using MGIT 960 with a critical concentration of 1 mg/L. The MIC of bedaquiline was determined using the proportion method. To identify genetic determinants...

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PMID: 28387862
DOI: 10.1093/jac/dkx094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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