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Article

Characteristic exploration of Mycobacterium tuberculosis isolated from patients with linezolid-treated multidrug-resistant tuberculosis.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Feb 2026

Kim Younghun, Lee Da-Gyum, Bae Jinyoung, Jung Jihee, Jeon Hyeongrin, Chung Myungguen, Park Jin-A, Ahn Kung, Mun Jae-Woo, Jang Younghoon, Lee Heedoo, Jang Jichan, Ryoo Sungweon

Abstract excerpt

SYNOPSIS: OBJECTIVES: Linezolid (LZD) is crucial for treating multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB); however, mutations related to LZD resistance still need to be characterised. This study investigated resistance-related mutations on a whole-genome scale in clinical isolates from patients with MDR/XDR TB who failed LZD treatment. METHODS: The phenotypic drug...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41160260
DOI: 10.1007/s10096-025-05319-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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