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Article

Genetic Mutation and Exosome Signature of Human Papilloma Virus Associated Oropharyngeal Cancer.

Scientific reports - 6 Apr 2017

Kannan Anbarasu, Hertweck Kate L, Philley Julie V, Wells Robert B, Dasgupta Santanu

Abstract excerpt

Human papilloma virus-16 (HPV-16) associated oropharyngeal cancer (HPVOPC) is increasing alarmingly in the United States. We performed whole genome sequencing of a 44 year old, male HPVOPC subject diagnosed with moderately differentiated tonsillar carcinoma. We identified new somatic mutation in MUC16 (A.k.a. CA-125), MUC12, MUC4, MUC6, MUC2, SIRPA, HLA-DRB1, HLA-A and HLA-B molecules. Increased protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28383029
DOI: 10.1038/srep46102
PMCID: PMC5382706

Genes

MUC16
MUC2
MUC4
MUC12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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