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Discovery and development of differentially methylated regions in human papillomavirus‐related oropharyngeal squamous cell carcinoma

6 Aug 2018

Abstract excerpt

Human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) exhibits a different composition of epigenetic alterations. In this study, we identified differentially methylated regions (DMRs) with potential utility in screening for HPV-positive OPSCC. Genome wide DNA methylation was measured using methyl-CpG binding domain protein-enriched genome sequencing (MBD-seq) in 50 HPV-positive OPSCC...

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Share to Cancer-related gene regulation
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PMID: 30070359
DOI: 10.1002/ijc.31778

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