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Article

The two-component system VicRK regulates functions associated with Streptococcus mutans resistance to complement immunity.

Molecular oral microbiology - 1 Oct 2017

Alves Livia A, Harth-Chu Erika N, Palma Thais H, Stipp Rafael N, Mariano Flávia S, Höfling José F, Abranches Jacqueline, Mattos-Graner Renata O

Abstract excerpt

Streptococcus mutans, a dental caries pathogen, can promote systemic infections upon reaching the bloodstream. The two-component system (TCS) VicRKSm of S. mutans regulates the synthesis of and interaction with sucrose-derived exopolysaccharides (EPS), processes associated with oral and systemic virulence. In this study, we investigated the mechanisms by which VicRKSm affects S. mutans susceptibility to...

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Source

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Identifiers

PMID: 28382721
DOI: 10.1111/omi.12183
PMCID: PMC5585069

Genes

GAPDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The two-component system VicRK regulates functions associated with Streptococcus mutans resistance to complement immunity.PMID 28382721Read ↗

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