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Article

The two-component system ScnRK of Streptococcus mutans affects hydrogen peroxide resistance and murine macrophage killing.

Microbes and infection - 1 Mar 2008

Chen Pei-Min, Chen Heng-Chang, Ho Chun-Ta, Jung Chiau-Jing, Lien Huei-Ting, Chen Jen-Yang, Chia Jean-San

Abstract excerpt

To survive macrophage killing is critical in the pathogenesis of viridians streptococci-induced infective endocarditis (IE). Streptococcus mutans, an opportunistic IE pathogen, generally does not survive well phagocytic killing in murine macrophage RAW 264.7 cells. A putative two-component system (TCS), ScnR/ScnK from S. mutans, was investigated to elucidate the mechanisms underlying bacteria-cellular interaction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18316220
DOI: 10.1016/j.micinf.2007.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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