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Modulation of Biofilm Exopolysaccharides by the Streptococcus mutans vicX Gene

21 Dec 2015

Abstract excerpt

The cariogenic pathogen Streptococcus mutans effectively utilizes dietary sucrose for the synthesis of exopolysaccharide, which act as a scaffold for its biofilm, thus contributing to its pathogenicity, environmental stress tolerance, and antimicrobial resistance. The two-component system VicRK of S. mutans regulates a group of virulence genes that are associated with biofilm matrix synthesis. Knockout of vicX...

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PMID: 26733973
DOI: 10.3389/fmicb.2015.01432

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