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The <i>Streptococcus mutans vicX</i> Gene Product Modulates <i>gtfB</i> / <i>C</i> Expression, Biofilm Formation, Genetic Competence, and Oxidative Stress Tolerance

18 Nov 2006

Abstract excerpt

Streptococcus mutans is considered one of the primary etiologic agents of dental caries. Previously, we characterized the VicRK two-component signal transduction system, which regulates multiple virulence factors of S. mutans. In this study, we focused on the vicX gene of the vicRKX tricistronic operon. To characterize vicX, we constructed a nonpolar deletion mutation in the vicX coding region in S. mutans UA159....

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PMID: 17114248
DOI: 10.1128/jb.01161-06

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The <i>Streptococcus mutans vicX</i> Gene Product Modulates <i>gtfB</i> / <i>C</i> Expression, Biofilm Formation, Genetic Competence, and Oxidative Stress TolerancePMID 17114248Read ↗

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