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Article

Investigation of a possible extended risk haplotype in the IL23R region associated with ankylosing spondylitis.

Genes and immunity - 1 Mar 2017

Roberts A R, Vecellio M, Cortes A, Knight J C, Cohen C J, Wordsworth B P

Abstract excerpt

The IL23R region on chromosome 1 exhibits complex associations with ankylosing spondylitis (AS). We used publicly available epigenomic information and historical genetic association data to identify a putative regulatory element (PRE) in the intergenic region between IL23R and IL12RB2, which includes two single-nucleotide polymorphisms (SNPs) independently associated with AS-rs924080 (P=2 × 10-3) and rs11578380...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28381868
DOI: 10.1038/gene.2017.5
PMCID: PMC5435965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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