Article
Single-nucleotide polymorphisms and expression of IL23R in Chinese ankylosing spondylitis patients.
Rheumatology international - 1 May 2010
Wang Xinwei, Huang Jinxian, Lin Zhiming, Liao Zetao, Li Chao, Wei Qiujing, Jiang Yingjuan, Zhao Like, Gu Jieruo
Abstract excerpt
The aim of this study was to investigate the association of single-nucleotide polymorphisms (SNPs) in IL23R with ankylosing spondylitis (AS) in Chinese Han population. Six SNPs were selected for analysis in AS patients and controls. The IL23R mRNA expression was detected using RT-PCR. The differences in the genotypes of rs11209032 and the differences in the genotypes and allele frequencies of rs6677188 between...
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