Article
Role of tumour-associated macrophages in oral squamous cells carcinoma progression: an update on current knowledge.
Diagnostic pathology - 5 Apr 2017
Petruzzi Maria Noel Marzano Rodrigues, Cherubini Karen, Salum Fernanda Gonçalves, de Figueiredo Maria Antonia Zancanaro
Abstract excerpt
BACKGROUND: Oral squamous cell carcinoma (OSCC) accounts over 90% of malignant neoplasms of the oral cavity. This pathological entity is associated to a high mortality rate that has remained unchanged over the past decades. Tumour-associated macrophages (TAMs) are believed to have potential involvement in OSCC progression. However, the molecular networks involved in communication between stroma and cancer cells...
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