Article
Involvement of extracellular vesicles in the macrophage-tumor cell communication in head and neck squamous cell carcinoma.
PloS one - 1 Jan 2019
Bellmunt Àngela Maria, López-Puerto Laura, Lorente Juan, Closa Daniel
Abstract excerpt
BACKGROUND: Exosomes are cell-derived vesicles that mediate cellular communication in health and multiple diseases, including cancer. However, its role in head and neck cancer has been poorly defined. Here, we investigated the relevance of exosomes in the signaling between larynx cancer cells and macrophages. METHODS: Exosomes from THP1 macrophages and BICR18 cells (a larynx squamous cell carcinoma cell line)...
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