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Article

Prevalence of low-level HIV-1 variants with reverse transcriptase mutation K65R and the effect of antiretroviral drug exposure on variant levels.

Antiviral therapy - 1 Jan 2011

Kozal Michael J, Chiarella Jennifer, St John Elizabeth P, Moreno Elizabeth A, Simen Birgitte B, Arnold Todd E, Lataillade Max

Abstract excerpt

BACKGROUND: It has been reported that treatment-naive individuals infected with HIV-1 subtype C may be more likely to harbour viral variants possessing a K65R reverse transcriptase gene mutation. The objectives of this study were to determine the prevalence of low-level K65R variants within different HIV-1 subtypes and to assess the effects of antiretroviral exposure on K65R variant levels. METHODS:...

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Source

Identifiers

PMID: 21900725
DOI: 10.3851/IMP1851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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