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Article

The transforming growth factor-β receptor genes and the risk of intracranial aneurysms.

International journal of stroke : official journal of the International Stroke Society - 1 Dec 2012

Ruigrok Ynte M, Baas Annette F, Medic Jelena, Wijmenga Cisca, Rinkel Gabriel J E

Abstract excerpt

BACKGROUND: Mutations in the receptor genes of the transforming growth factor β pathway, TGFBR1 and TGFBR2, cause syndromes with thoracic aortic aneurysms, while genetic variants in TGFBR1 and TGFBR2 are associated with abdominal aortic aneurysms. The transforming growth factor-β pathway may be involved in aneurysm development in general. Aims To analyze whether genetics variants in TGFBR1 and TGFBR2 are also...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21978186
DOI: 10.1111/j.1747-4949.2011.00615.x

Genes

TGFBR1
TGFBR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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