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CAN the variants in the THADA and ADAMST9 genes be common risk factors for type 2 diabetes development and obesity.

Molecular biology reports - 19 Jun 2026

Erkoç-Kaya Dudu, Arikoglu Hilal, Gokturk Fatma, Iscioglu Funda, Ipekci Suleyman Hilmi

Abstract excerpt

BACKGROUND: Obesity is an important risk factor for Type 2 Diabetes (T2D) as approximately 90% of T2D patients are obese. The single nucleotide polymorphisms (SNPs) rs4607103 (C˃T) in the ADAMTS9 gene and rs7578597 (T˃C) in the THADA gene were identified as two novel T2D risk loci. However, studies investigating the associations of these variants with T2D and obesity are limited, and little is known about the...

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Identifiers

PMID: 42319597
DOI: 10.1007/s11033-026-12184-0

Genes

ADAMTS9

Variants

rs4607103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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