Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.

Journal of the National Cancer Institute - 1 Mar 2017

Ma Ran, Karthik Govindasamy-Muralidharan, Lövrot John, Haglund Felix, Rosin Gustaf, Katchy Anne, Zhang Xiaonan, Viberg Lisa, Frisell Jan, Williams Cecilia, Linder Stig, Fredriksson Irma, Hartman Johan

Abstract excerpt

Background: Breast cancer cells with tumor-initiating capabilities (BSCs) are considered to maintain tumor growth and govern metastasis. Hence, targeting BSCs will be crucial to achieve successful treatment of breast cancer. Methods: We characterized mammospheres derived from more than 40 cancer patients and two breast cancer cell lines for the expression of estrogen receptors (ERs) and stem cell markers....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estradiol
Share to Estrogen Receptor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fulvestrant

Share to Glycolysis

Share to MCF-7 Cells

Share to Spheroids, Cellular

Share to Tamoxifen

Share to Triple Negative Breast Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 28376210
DOI: 10.1093/jnci/djw236
PMCID: PMC5441302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.PMID 28376210Read ↗

Identification of Distinct Breast Cancer Stem Cell Populations Based on Single-Cell Analyses of Functionally Enriched Stem and Progenitor Pools.Semantic proximity Read ↗

Estrogen Receptor β4 Regulates Chemotherapy Resistance and Induces Cancer Stem Cells in Triple Negative Breast CancerSemantic proximity Read ↗

Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines.Semantic proximity Read ↗

Activation of estrogen receptor beta signaling reduces stemness of glioma stem cellsSemantic proximity Read ↗

Cancer stem cells are prevalent in the basal-like 2 and mesenchymal triple-negative breast cancer subtypes in vitroSemantic proximity Read ↗

Research Resource: Global Identification of Estrogen Receptor β Target Genes in Triple Negative Breast Cancer CellsSemantic proximity Read ↗

Contrasting Hypoxic Effects on Breast Cancer Stem Cell Hierarchy Is Dependent on ER-α StatusSemantic proximity Read ↗

Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cellsSemantic proximity Read ↗

Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast CancerSemantic proximity Read ↗

Estrogen Signals through ERβ in Breast Cancer; What We Have Learned since the Discovery of the ReceptorSemantic proximity Read ↗

Insights into the Role of Estrogen Receptor β in Triple-Negative Breast CancerSemantic proximity Read ↗

RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.