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Article

Identification of Distinct Breast Cancer Stem Cell Populations Based on Single-Cell Analyses of Functionally Enriched Stem and Progenitor Pools.

Stem cell reports - 12 Jan 2016

Akrap Nina, Andersson Daniel, Bom Eva, Gregersson Pernilla, Ståhlberg Anders, Landberg Göran

Abstract excerpt

The identification of breast cancer cell subpopulations featuring truly malignant stem cell qualities is a challenge due to the complexity of the disease and lack of general markers. By combining extensive single-cell gene expression profiling with three functional strategies for cancer stem cell enrichment including anchorage-independent culture, hypoxia, and analyses of low-proliferative, label-retaining cells...

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Identifiers

PMID: 26771357
DOI: 10.1016/j.stemcr.2015.12.006
PMCID: PMC4719187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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