Article
Low Variability and Stable Frequency of Common Haplotypes of the TP53 Gene Region in Colorectal Cancer Patients in a Slovak Population.
Anticancer research - 1 Apr 2017
Škereňová Mária, Halašová Erika, Matáková Tatiana, Jesenská Ľubica, Jurečeková Jana, Šarlinová Miroslava, Čierny Daniel, Dobrota Dušan
Abstract excerpt
AIM: To test the association between common TP53 haplotypes and colorectal cancer (CRC) development. PATIENTS AND METHODS: A total of 277 CRC patients and 167 healthy volunteers were included in the study. Common TP53 haplotypes were estimated from eight single-nucleotide polymorphisms (SNPs) (rs1614984, rs77697176, rs12947788, rs1800372, rs2909430, , and ). Stepwise haplotype trend...