Article
Vascular endothelial growth factor (VEGF) gene polymorphisms may influence the efficacy of thalidomide in multiple myeloma.
International journal of cancer - 1 Sept 2012
Andersen Niels F, Vogel Ulla, Klausen Tobias W, Gimsing Peter, Gregersen Henrik, Abildgaard Niels, Vangsted Annette J
Abstract excerpt
Vascular endothelial growth factor (VEGF) is a potent proangiogenic factor. Several single nucleotide polymorphisms (SNPs) in the VEGF gene with influence on VEGF expression have been described. In multiple myeloma, VEGF stimulates angiogenesis which is correlated with disease progression and prognosis. In this study, we evaluated the association between genetic variations in the VEGF gene in patients with...
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